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KMID : 1038120200530060746
Clinical Endoscopy
2020 Volume.53 No. 6 p.746 ~ p.749
Rare and Fatal Gastrointestinal Mucormycosis (Zygomycosis) in a COVID-19 Patient: A Case Report
do Monte Epifanio Silvino Junior

dos Santos Marcos Eduardo Lera
Ribeiro Igor Braga
de Oliveira Luz Gustavo
Baba Elisa Ryoka
Hirsch Bruno Salomao
Funari Mateus Pereira
De Moura Eduardo Guimaraes Hourneaux
Abstract
The novel coronavirus disease (COVID-19) quickly spread to all continents. However, data regarding all the signs and symptoms of COVID-19 are insufficient. Patients with COVID-19 might present higher susceptibility to fungal coinfections. Mucormycosis is a rare and often life-threatening fungal disease characterized by vascular invasion by hyphae, resulting in thrombosis and necrosis. This is the first case report of mucormycosis in a COVID-19 patient. An 86-year-old male patient was admitted to the emergency room with acute diarrhea, cough, dyspnea, and fever from 5 days prior. Blood tests revealed a hemoglobin level of 14.3 mg/dL. Five days following the admission, the patient presented with melena and a hemoglobin level of 5.6 mg/dL. A transfusion of three units of red blood cells was required. Esophagogastroduodenoscopy (EGD) revealed two giant gastric ulcers with necrotic debris and a deep hemorrhagic base without active bleeding. Furthermore, biopsies confirmed mucormycosis. Despite intensive care, the patient died 36 hours after the EGD.
KEYWORD
Coronavirus infections, Gastroenteritis, Gastrointestinal hemorrhage, Mucormycosis, Zygomycosis
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